Hiring

Dr. Kun-Che Chang’s laboratory is seeking a highly motivated full-time postdoctoral associate at the Department of Ophthalmology, University of Pittsburgh. The Chang Lab studies the regulatory mechanisms of retinal differentiation and molecular mechanisms that lead to blindness, especially in glaucoma. The Chang Lab aims to utilize human stem cell and genetic therapies to treat retinal ganglion cell (RGC) loss and optic neuropathies. In particular, we use human retinal organoids to study retinal development and use rodent model to investigate axon regeneration. We further utilize single-cell RNA sequencing to analyze the molecular regulation in retinal organoid and rodent retina. Our aim is to discover the most effective and potent molecules, characterize their underlying mechanisms, and to develop an efficacious and safe treatment regimen that can be further tested in large animals and clinical trials.

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The University of Pittsburgh provides an excellent environment to support diversity and international scientists. U Pitt ranks number 4 for NIH funding in the US. Pittsburgh is a vibrant and affordable city that offers a multitude of local amenities, including major league sports, a dynamic cultural district, and old-world neighborhood charm. Rated the “Most Livable City” in the US by Forbes Magazine and the Economist, Pittsburgh is a great place to live and work.

 

The successful postdoc will be involved in an ongoing study of stem cell and animal studies. Qualified candidates are welcome to submit a PDF file including a cover letter describing research interest, strength and previous accomplishments (1 page), CV and contacts of at least three references to Dr. Chang (kcchang@pitt.edu).

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Salary: $50,000/yr or more based on experience plus Fringe benefits including health, dental and vision insurances.

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Qualifications of the candidate:

• Ph.D. and/or M.D./Ph.D. in stem cell biology, neuroscience, developmental biology or relevant field of biomedical sciences, or M.D. of Ophthalmology.

• At least one first-author publication in one of the following fields: ophthalmology/vision science, developmental biology, stem cell biology.

• A highly motivated and responsible scientist with demonstrated capability of working independently with strong troubleshooting skills, quick learning and teamwork spirit.

• Experience in multiple of the following techniques is preferred: animal handling and breeding, mouse injection and dissection, cell culture, wet bench, confocal imaging.