Publications

Chang KC#,*,Hertz JY#, Zhang X#, Jin XL, Shaw P, Derosa BA, Li JY, Venugopalan P, Valenzuela DA, Patel RD, Russano KR,     Alshamekh SA, Sun C, Tenerelli K, Li C, Velmeshev D, Cheng Y, Boyce TM, Dreyfuss A, Uddin MS, Muller KJ, Dykxhoorn DM and Goldberg JL “Novel regulatory mechanisms for the SoxC transcriptional network required for visual pathway development” J Neurosci. 2017, 37(19):4967-4981 (# Co-first author)

Chang KC*, SunC, Cameron EG, Madaan A, Wu S, Xia X, Zhang X, Tenerelli K, Nahmou M, Knasel CM, Russano KR, Hertz J and Goldberg JL“Opposing effects of growth and differentiation factor in cell fate specification” Current Biology. 2019, 29(12):1963-1975.

Chang KC*, Bian M, Xia X, Madaan A, Sun C, Wang Q, Li L, Nahmou M, Noro T, Yokota S, Galvao J, Kreymerman A, Tanasa B, Hu Y, Goldberg JL* “Post-translational modification of Sox11 regulates RGC survival and axon regeneration” eNeuro, 2021, 8(1).

Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard J, Liau LM, Goldberg JL, Monje M*# and Gutmann DH*# “NF1 mutation drives neuronal activity-dependent optic glioma initiation” Nature. 2021, 594(7862):277-282.

Luo Z#, Chang KC#, Wu S, Sun C, Xia X, Nahmou M, Bian M, Wen RR, Zhu Y, Shah S, Tanasa B, Wernig M, Goldberg JL* "Directly induced human retinal ganglion cells mimic fetal RGCs and are neuroprotective after transplantation in vivo" Stem cell reports, 2022, 17(12):2690-2703 (#Co-first author).

Huang YK, Liu CC, Cheng HC, Meadows C and Chang KC* “The influence of aldose reductase in beta-amyloid induced microglia activation. , Int J Mol Sci. 2022, 23(23):15088.

Rao M, Huang YK, Liu CC, Meadows C, Cheng HC, Zhou M, Chen YC, Xia X, Goldberg JL, Williams AM, Kuwajima T and Chang KC* “Aldose reductase inhibition decelerates optic nerve degeneration by suppressing retinal microglia activation. Scientific Reports. 2023, 13(1):5592.

Cameron EG, Nahmou M, Toth AB, Heo L, Tanasa B, Dalal R, Yan W, Nallagatla P, Xia X, Hay S, Knasel C, Stiles TL, Douglas C, Atkins M, Sun C, Ashouri M, Bian M, Chang KC, Russano K, Shah S, Woodworth MB, Galvao J, Nair RV, Kapiloff MS, Goldberg JL.“A molecular switch for neuroprotective astrocyte reactivity” Nature. 2024, in press.

Wu S#, Chang KC#*, Goldberg JL “Retinal Cell Fate Trajectory” Trends in Neurosci. 2018, 41(4):165-167. (# Co-first author).

Chang KC, Liu PF, Chang CH, Lin YC, Chen YJ, Shu CW* “The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases” Cell Biosci. 2022,12(1):1.

Lo J, Mehta K, Dhillon A, Huang YK, Luo Z, Nam MH*, Aldiri I*, Chang KC* “Therapeutic strategies for glaucoma and optic neuropathies”. Molecular Aspects of Medicine. 2023, 94:101219.