Publications

Research articles (Selective)

Luo Z#, Chang KC#, Wu S, Sun C, Xia X, Nahmou M, Bian M, Wen RR, Zhu Y, Shah S, Tanasa B, Wernig M, Goldberg JL* "Directly induced human retinal ganglion cells mimic fetal RGCs and are neuroprotective after transplantation in vivo" Stem cell reports, 2022, 17(12):2690-2703 (#Co-first author).
Rao M, Huang YK, Liu CC, Meadows C, Cheng HC, Zhou M, Chen YC, Xia X, Goldberg JL, Williams AM, Kuwajima T and Chang KC* “Aldose reductase inhibition decelerates optic nerve degeneration by suppressing retinal microglia activation" Scientific Reports. 2023, 13(1):5592.
Luo Z*, Shah S, Tanasa B, Chang KC*, Goldberg JL. "Gene regulatory roles of growth and differentiation factors in retinal development" iScience. 2024, 27(6):110100.
Wang S, Chen CY, Liu CC, Stavropoulos D, Rao M, Petrash JM, Chang KC*. "GDF-15 Attenuates the Epithelium-Mesenchymal Transition and Alleviates TGFβ2-Induced Lens Opacity" Transl Vis Sci Technol. 2024, 13(7):2.
Rao M, Luo Z, Liu CC, Chen CY, Wang S, Nahmou M, Tanasa B, Virmani A, Byrne L, Goldberg JL, Sahel JA, Chang KC*. “Tppp3 is a Novel Molecule for Retinal Ganglion Cell Identification and Optic Nerve Regeneration” Acta Neuropathol Commun. 2024,12(1):204.

Chang KC, Liu PF, Chang CH, Lin YC, Chen YJ, Shu CW* “The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases” Cell Biosci. 2022,12(1):1.
Lo J, Mehta K, Dhillon A, Huang YK, Luo Z, Nam MH*, Aldiri I*, Chang KC* “Therapeutic strategies for glaucoma and optic neuropathies”. Molecular Aspects of Medicine. 2023, 94:101219.
Rao M, Chang KC* "Aldose reductase is a potential therapeutic target for neurodegeneration" Chem Biol Interact. 2024, 389:110856.

Chang KC and Petrash JM* “Aldo-Keto Reductases: Multifunctional Proteins as Therapeutic Targets in Diabetes and Inflammatory Disease” Advances in Experimental Medicine and Biology. 2018, Springer, 1032: 173–202.
Luo Z, Nahmou M and Chang KC* “Stem Cell Therapies for Glaucoma and Optic Neuropathy” Advances in Stem Cell Biology – Recent Advances in iPSCs for Therapy. 2021, Elsevier, Volume 3, Chapter 6.
Rao M, Liu CC, Wang S, Chang KC* “Generating ESC-derived RGCs for cell replacement therapy” Methods in Molecular Biology – Ocular Regeneration: Methods and Protocols. 2024, Springer, 2848:187-196.